Controllability on Brain Networks

Neuroscientific investigations seek to reveal how neural systems perform complex functions, how those systems and functions are altered in disease states, and how therapeutic interventions can be used to redirect these alterations. In essence, all three lines of investigation seek to address how neural systems move along dynamic trajectories: of cogni- tive function, disease, or recovery. While we have begun to make headway in a few specific examples of dynamic trajectories (e.g., movement, decision-making , epilepsy), the fundamental and therefore generalizable mechanisms of these movements have remained elusive.