Medial temporal lobe (MTL) is generally thought to be a principal site of long term memory (LTM) process, and isn’t usually associated with short term memory (STM). Some recent work have suggested a role for MTL in STM when binding … Continue reading
Quantification of medial temporal lobe (MTL) cortices, including entorhinal cortex (ERC) and perirhinal cortex (PRC), from in vivo MRI is desirable for studying the human memory system as well as in early diagnosis and monitoring of Alzheimer’s disease. However, ERC … Continue reading
The human perirhinal cortex (PRC) plays critical roles in episodic and semantic memory and visual perception. The PRC consists of Brodmann areas 35 and 36 (BA35, BA36). In Alzheimer’s disease (AD), BA35 is the first cortical site affected by neurofibrillary … Continue reading
In our recent publication in Cerebral Cortex we compared in vivo and ex vivo MRI scans of the human hippocampus and evaluated to ability to match information between the two modalities. We were able to validate several of the features … Continue reading
Daniel Adler’s MICCAI 2016 paper “Probabilistic atlas of the human hippocampus combining ex vivo MRI and histology” describes substantial progress on building a comprehensive atlas of the human hippocampus that combines ultra-high resolution ex vivo MRI and serial histological imaging. … Continue reading
An integrated methodology for imaging, segmenting, modeling, and deriving computationally-predicted pressure-derived mitral leaflet stresses is presented and points the way towards intraoperative and periprocedural guidance from morphometric and stress modeling of the mitral valve. In vivo human mitral valves are … Continue reading
Tract specific Analysis (TSA) uses continuous medial modeling for structure- specific analysis of diffusion in sheet-like white matter tracts in the human brain. The medial geometry provides both a skeleton surface (the medial surface) and two “spoke” vectors from the … Continue reading
Abstract: Responses to acute stressors are determined in part by stress history. For example, a history of chronic stress results in facilitated responses to a novel stressor and this facilitation is considered to be adaptive. We previously demonstrated that repeated … Continue reading
[Could not find the bibliography file(s) Purpose: To evaluate the relationships between cerebral blood flow and other magnetic resonance (MR) imaging based measures such as fractional anisotropy, magnetic transfer ratio, cortical thickness and mean resting state BOLD signal in typically … Continue reading
The aims of this collaborative project with the Computational Imaging Lab at the Pompeu Fabra University are to use a medial model of the myocardium to generate stronger shape priors for segmentation, richer features for shape analysis and a shape-based … Continue reading