Relating brain anatomy and cognitive ability using a multivariate multimodal framework

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Linking structural neuroimaging data from multiple modalities to cognitive performance is an important challenge for cognitive neuroscience. In this study we examined the relationship between verbal fluency performance and neuroanatomy in 54 patients with frontotemporal degeneration (FTD) and 15 age-matched … Continue reading

Sparse Dimensionality Reduction for Medical Imaging

The complex and high-dimensional nature of medical images makes them difficult to incorporate into traditional linear model-based statistical analysis.  One way of simplifying analysis of medical images is to use a dimensionality reduction technique.  We designed a dimensionality reduction technique … Continue reading

Associations between children’s socioeconomic status and prefrontal cortical thickness

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Childhood socioeconomic status (SES) predicts executive function performance and measures of prefrontal cortical function, but little is known about its anatomical correlates. Structural MRI and demographic data from a sample of 283 healthy children from the NIH MRI Study of … Continue reading