Accounting for the Confound of Meninges in Segmenting Entorhinal and Perirhinal Cortices in T1-weighted MRI

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Quantification of medial temporal lobe (MTL) cortices, including entorhinal cortex (ERC) and perirhinal cortex (PRC), from in vivo MRI is desirable for studying the human memory system as well as in early diagnosis and monitoring of Alzheimer’s disease. However, ERC … Continue reading

Multi-Template Analysis of Human Perirhinal Cortex in Brain MRI: Explicitly Accounting for Anatomical Variability

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The human perirhinal cortex (PRC) plays critical roles in episodic and semantic memory and visual perception. The PRC consists of Brodmann areas 35 and 36 (BA35, BA36). In Alzheimer’s disease (AD), BA35 is the first cortical site affected by neurofibrillary … Continue reading

Regional Thickness Measurement of Extra-hippocampal Medial Temporal Lobe Structures

Extra-hippocampal medial temporal lobe (ehMTL) structures, which consists of entorhinal (ERC) and perirhinal (PRC) cortices, receives increasing attention because they are amongst the earliest sites affected by Alzheimer`s Disease (AD) pathology and due to their important and complex role in episodic … Continue reading